LONDON Jaquiski Tartt Womens Jersey , Sept. 13 (Xinhua) -- Researchers at the University of Liverpool have revealed they have made a breakthrough that could lead to a cure being developed for the Ebola virus currently sweeping through West Africa.
The university said on Thursday that experts stumbled across an existing drug used in the treatment of severe heart disease, which could be adapted to fight the deadly Ebola virus.
A team from the Health Protection Research Unit in Emerging Infections, based at the University of Liverpool's Institute of Infection and Global Health, have been investigating new ways to treat Ebola. The team is behind the potential breakthrough in the global race to find a treatment.
In collaboration with Public Health England, the team has been looking at how Ebola virus hijacks proteins inside cells, and then seeking ways to stop this from happening.
They looked at what proteins inside a cell are critical for the functions of Ebola virus and are hijacked by the virus to help with infection. One of the proteins they have targeted is known as VP24. This protein disrupts signalling in infected human cells and disrupts the body's immune system and the fight against the virus.
From there the Liverpool team looked at whether any existing drugs already block the function of this particular protein. They found the heart drug, ouabain, when administered can reduce the virus' replication.
The team said further testing needs to be done, but as the heart drug is already in use, much of the work to test whether it is safe for humans has already been completed. This, they said, would potentially speed up the time it could take get the treatment to Ebola patients in need.
The study was led by Professor Julian Hiscox from the University of Liverpool's Institute of Infection and Global Health and Professor Roger Hewson at Public Health England.
Prof Hiscox said:"This study shows how existing therapeutics can be identified and potentially repurposed for anti-viral therapy. The technique of using existing and tested drugs for a different purpose can save considerable time and ultimately, lives."
The British Health Protection Research Unit in Emerging Infections opened in April of this year.
Professor Tom Solomon, director of the health protection research unit, said: "This is a fantastic piece of work by the Liverpool team, in collaboration with colleagues. It may be an important step to help us tackle this devastating disease which is spreading across West Africa".
The study used specialist facilities which allowed them to work with the Ebola virus safely, under conditions of "high containment".
Planning to undergo a root canal treatment? Before you fully consider this dental option, read on to know several facts about this particular treatment.
What is it exactly? Root canal refers to the gap or area within the root of your tooth. It particularly points to the natural cavity that is built in the central area of your tooth. The pulp chamber, on the other hand, refers to the soft area that is located within the coronal tooth area. There are also several tooth nerves that are connected in the root canal.
Who should undergo such procedure? This treatment is advised to those who have bad case or tooth decay or early infection. This is to avoid further worsening of the infection and the formation of any abscesses.
How does the process works? The procedure is meant to save the tooth from becoming further infected or decayed. Otherwise, the affected area needs to be removed to avoid further complications. Nerve and pulp inside the tooth need to be removed so the area can be thoroughly cleaned and sealed.
Is the procedure painful? Contrary to popular belief, this type of treatment has very tolerable level of pain. Besides, dental clinics like <"http:www.brisbanesmilecentre">Brisbane Smile Centre perform the procedure by numbing first the area to be treated. After the medicine has worn off, you may expect some tenderness in the treated area, and this is perfectly normal because of the natural tissue inflammation. This is also typical if you’ve experienced pain or infection before undergoing the treatment. Over-the-counter drugs are usually taken to control the sensitivity and post-treatment pain.
What are the usual symptoms that indicate the need to undergo this treatment? Common symptoms include having a severe case of tooth pain when chewing or when you apply pressure to your teeth. You also become highly sensitive to pain when exposed to hot or cold temperatures. You can also consider the treatment if you constantly experience having a pimple on your gums. Sometimes, tooth discoloration is also among the symptoms that can indicate the need to undergo this procedure. There’s also the common swelling experienced in the gum area.
Why is it important to undergo such treatment? This dental procedure is highly recommended because of several reasons. If the nerve tissues and pulp in your tooth are damaged, there is a high chance for bacteria to grow and multiply in the pulp area. This situation can lead to infection as well as formation of abscesses. Abscessed tooth is usually formed when the infection has already scattered up to the ends of your tooth roots. Infection in this area can also seriously lead to swelling that may affect even your neck and face areas. There is also a risk of losing parts of your bone around the root’s tip because of the infection.